Contactul. Lwowska 1, 87-100 Toruń
tel.: +48 56 611-25-05
fax: +48 56 611-47-72
e-mail: dwnbiw@umk.pl
obrazek nr 1 obrazek nr 2 obrazek nr 3 obrazek nr 4 obrazek nr 5

Publications

Selected publications in peer-reviewed journals

2024

  1. Linowiecka K., J. Szpotan, M. Godlewska, D. Gaweł, E. Zarakowska, D. Gackowski, A.A. Brożyna, M. Foksiński: Selective Estrogen Receptor Modulators’ (SERMs) Influence on TET3 Expression in Breast Cancer Cell Lines with Distinct Biological Subtypes. Int J Mol Sci.  25 (16): 8561. doi: 10.3390/ijms25168561 (2024)
  2. Slominski R.M., T.K. Kim, Z. Janjetovic, A.A. Brożyna, E. Podgorska, K.M. Dixon, R.S. Mason, R.C. Tuckey, R. Sharma, D.K. Crossman, C. Elmets, C. Raman, A.M. Jetten, A.K. Indra, A.T. Slominski: Malignant Melanoma: An Overview, New Perspectives, and Vitamin D Signaling. Cancers (Basel). 16 (12): 2262. doi: 10.3390/cancers16122262 (2024)
  3. Madej E., A. Lisek, A.A. Brożyna, A. Cierniak, N. Wronski, M. Deptula, A. Wardowska, A. Wolnicka-Glubisz: The involvement of RIPK4 in TNF-α-stimulated IL-6 and IL-8 production by melanoma cells. J Cancer Res Clin Oncol. 150 (4): 209. doi: 10.1007/s00432-024-05732-3 (2024)
  4. Wronski N., E. Madej, M. Grabacka, A.A. Brożyna, A. Wolnicka-Glubisz: RIPK4 downregulation impairs Wnt3A-stimulated invasiveness via Wnt/β-catenin signaling in melanoma cells and tumor growth in vivo. Cell Signal. 113: 110938. doi: 10.1016/j.cellsig.2023.110938 (2024)
  5. Linowiecka K., J. Guz, T. Dziaman, O. Urbanowska-Domańska, E. Zarakowska, A. Szpila, J. Szpotan, A. Skalska-Bugała, P. Mijewski, A. Siomek-Górecka, R. Różalski, D. Gackowski, R. Oliński, M. Foksiński: The level of active DNA demethylation compounds in leukocytes and urine samples as potential epigenetic biomarkers in breast cancer patients. Sci Rep. 14 (1): 6481. doi: 10.1038/s41598-024-56326-5 (2024)

2023

  1. Madej E., A.A. Brożyna, A. Adamczyk, N. Wronski, A. Harazin-Lechowska, A. Muzyk, K. Makuch, M. Markiewicz, J. Rys, A. Wolnicka-Glubisz: Vemurafenib and Dabrafenib Downregulates RIPK4 Level. Cancers (Basel). 15 (3): 918. doi: 10.3390/cancers15030918 (2023)
  2. Möller J.K.S., K. Linowiecka, M. Gagat, A.A. Brożyna, m. Foksiński, A. Wolnicka-Glubisz, E. Pyza, R.J. Reiter, M.K. Tulic, AT Slominski, K. Steinbrink, K. Kleszczyński: Melanogenesis Is Directly Affected by Metabolites of Melatonin in Human Melanoma Cells. Int J Mol Sci. 24 (19): 14947. doi: 10.3390/ijms241914947 (2023)
  3. Guz J., E. Zarakowska, P. Mijewski, A. Wasilow, J. Szpotan, M. Foksinski, B. Brzoszczyk, D. Gackowski, P. Jarzemski, R. Olinski: Unprecedentedly High Level of Intracellular Vitamin C and DNA Epigenetic Marks in Prostate: Relevant for Male Fertility? Cell Physiol Biochem. 57 (4): 200-211. doi: 10.33594/000000638 (2023)
  4. Samra T., T. Gomez-Gomez, K. Linowiecka, A. Akhundlu, G. Lopez de Mendoza, M. Gompels, W.W. Lee, J. Gherardini, J. Chéret, R. Paus: Melatonin Exerts Prominent, Differential Epidermal and Dermal Anti-Aging Properties in Aged Human Eyelid Skin Ex Vivo. Int J Mol Sci. 24 (21): 15963. doi: 10.3390/ijms242115963 (2023)
  5. Linowiecka K., A.T. Slominski, R.J. Reiter, M. Böhm, K. Steinbrink, R. Paus, K. Kleszczyński: Melatonin: A Potential Regulator of DNA Methylation. Antioxidants (Basel). 12(6):1155. doi: 10.3390/antiox12061155 (2023)
  6. Holtkamp C.E., D. Warmus, K. Bonowicz, M. Gagat, K. Linowiecka, A. Wolnicka-Glubisz, R.J. Reiter, M. Böhm, A.T. Slominski, K. Steinbrink, K. Kleszczyński: Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes. Metabolites. 13 (7): 861. doi: 10.3390/metabo13070861 (2023)
  7. Neesen F., N. Wronski, K. Linowiecka, C. Becker, V. Raker, R. Dreier, M.K. Tulic, A.T. Slominski, A. Wolnicka-Glubisz, K. Steinbrink, M. Böhm, K. Kleszczynski: Melatonin enhances BRAF/MEK inhibitors-induced disturbances in mitochondrial homeostasis and oncogenic pathways in human melanoma. J Invest Dermatol. 143 (5): 1182 10.1016/j.jid.2023.03.1196 (2023)

2022

  1. Brożyna A.A., L. Poliseno, A.T. Slominski, Editorial: Role of pigmentation in melanoma. Front Oncol. 23 (12): 1084717. doi: 10.3389/fonc.2022.1084717 (2022)
  2. Brożyna A.A., R.M. Slominski, B. Nedoszytko, M.A. Żmijewski, A.T. Slominski: Vitamin D signaling in psoriasis: pathogenesis and therapy. Int J Mol Sci. 23 (15): 8575. doi: 10.3390/ijms23158575 (2022)
  3. Piliszek R., A.A. Brożyna, W.R. Rudnicki: Computational Analysis Identifies Novel Biomarkers for High-Risk Bladder Cancer Patients. Int J Mol Sci. 23 (13): 7057. doi: 10.3390/ijms23137057 (2022)
  4. Fandzloch M., T. Jędrzejewski, J. Wiśniewska, J. Sitkowski, L. Dobrzańska, A.A. Brożyna, S. Wrotek. Sawhorse-type ruthenium complexes with triazolopyrimidine ligands – what do they represent in terms of cytotoxic and CORM compounds? Dalton Trans. 51 (22): 8804-8820. doi: 10.1039/d1dt04294g (2022)
  5. Slominski R.M., T. Sarna, P.M. Płonka, C. Raman, A.A. Brożyna, A.T. Slominski: Melanoma, Melanin, and Melanogenesis: The Yin and Yang Relationship. Front Oncol. 12: 842496. doi: 10.3389/fonc.2022.842496 (2022)
  6. Brożyna A.A., M.A. Żmijewski, K. Linowiecka, T.K. Kim, R.M. Slominski, A.T. Slominski: Disturbed expression of vitamin D and retinoic acid-related orphan receptors α and γ and of megalin in inflammatory skin diseases. Exp Dermatol. 31 (5): 781-788. doi: 10.1111/exd.14521 (2022)
  7. Skalska-Bugala A., M. Starczak, Ł. Szukalski, M. Gawronski, A. Siomek-Gorecka, J. Szpotan, A. Labejszo, E. Zarakowska, A. Szpila, A. Jachalska, A. Szukalska, M. Kruszewski, A. Sadowska, A. Wasilow, P. Baginska, J. Czyz 2, R. Olinski, R. Rozalski, D. Gackowski: Diagnostic and Prognostic Power of Active DNA Demethylation Pathway Intermediates in Acute Myelogenous Leukemia and Myelodysplastic Syndromes. Cells. 11 (5): 888. doi: 10.3390/cells11050888 (2022)
  8. Kuźbicki Ł., A.A. Brożyna: The detectability of intraepidermal melanocytes-A narrative review of immunohistochemical studies. J Cutan Pathol. 49 (12): 1074-1089. doi: 10.1111/cup.14295 (2022)
  9. Kuźbicki Ł., A.A. Brożyna: The markers auxiliary in differential diagnosis of early melanomas and benign nevi sharing some similar features potentially leading to misdiagnosis – a review of immunohistochemical studies. Cancer Invest. 40 (10): 852-867. doi: 10.1080/07357907.2022.2134415 (2022)

2021

  1. Madej E., D. Ryszawy, A.A. Brożyna, M. Czyż, J. Czyż, A. Wolnicka-Głubisz: Deciphering the functional role of RIPK4 in melanoma. Int J Mol Sci. 22 (21): 1-21. doi: 10.3390/ijms222111504 (2021)
  2. Rozalski R, D. Gackowski, A. Skalska-Bugala, M. Starczak, A. Siomek-Gorecka, E. Zarakowska, M. Modrzejewska, T. Dziaman, A. Szpila, K. Linowiecka, J. Guz, J. Szpotan, M. Gawronski, A. Labejszo, L. Gackowska, M. Foksinski, E. Olinska, A. Wasilow, A. Koltan, J. Styczynski, R. Olinski: The urinary excretion of epigenetically modified DNA as a marker of pediatric ALL status and chemotherapy response. Sci Rep. 11 (1): 21345.  doi: 10.1038/s41598-021-00880-9 (2021)
  3. Artemov A.V., S. Zhenilo, D. Kaplun, A. Starshin, A. Sokolov, A.M. Mazur, J. Szpotan, M. Gawronski, M. Modrzejewska, D. Gackowski, E.B. Prokhortchouk: An IDH-independent mechanism of DNA hypermethylation upon VHL inactivation in cancer. Epigenetics. 1-12. doi: 10.1080/15592294.2021.1971372 (2021)
  4. Pawlikowska M., T. Jędrzejewski, A.T. Slominski, A.A. Brożyna, S. Wrotek: Pigmentation Levels Affect Melanoma Responses to Coriolus versicolor Extract and Play a Crucial Role in Melanoma-Mononuclear Cell Crosstalk. Int J Mol Sci. 22 (11): 5735. doi: 10.3390/ijms22115735 (2021)
  5. Kaczmarek-Szczepańska B., J. Ostrowska, J. Kozłowska, Z. Szota, A.A. Brożyna, R. Dreier, R.J. Reiter, A.T. Slominski, K. Steinbrink, K. Kleszczyński: Evaluation of Polymeric Matrix Loaded with Melatonin for Wound Dressing. Int J Mol Sci. 22 (11): 5658. doi: 10.3390/ijms22115658 (2021)
  6. Nowak I., A.A. Brożyna, M. Zabłocka, S. Student, M. Durbas, B. Bugara, H. Rokita: MCPIP1 expression positively correlates with melanoma-specific survival of patients, and its overexpression affects vital intracellular pathways of human melanoma cells. Mol Carcinog. doi: 10.1002/mc.23286 (2021)
  7. Kuźbicki Ł., A.A. Brożyna: Expression of cyclooxygenase-2 in human epithelial skin lesions – a systematic review of immunohistochemical studies. Appl Immunohistochem Mol Morphol. 29 (3): 163-174 (2021)

2020

  1. Brożyna A.A., T.-K. Kim, M. Zabłocka, W. Jóźwicki, J. Yue, R.C. Tuckey, A. Jetten, A.T. Slominski: Association between vitamin D, retinoic acid-related orphan receptors and vitamin D hydroxyderivatives in ovarian cancer. Nutrients. 12 (11): E3541. doi: 10.3390/nu12113541 (2020)
  2. Linowiecka K., M. Foksiński, A.A. Brożyna: Vitamin C transporters and their implications in carcinogenesis. Nutrients. 12: 3869. doi:10.3390/nu12123869 (2020)
  3. Zarychta E., K. Lepinay, S. Szubert, J. Jóźwicki, J. Misiak, A.A. Brożyna, K. Kosinska-Kaczynska, A. Lewandowska, E. Malicka, A. Makarewicz, P. Rhone, W. Jóźwicki: Wilms’ tumor 1 antigenimmunoreactivity in epithelial ovarian cancer – diagnostic and prognostic value. Folia Histochem Cytobiol. 58 (3): 198-207. doi: 10.5603/FHC.a2020.0022  (2020)
  4. Pawlikowska M., T. Jędrzejewski, A.A. Brożyna, S. Wrotek: Protein-Bound Polysaccharides from Coriolus Versicolor Induce RIPK1/RIPK3/MLKL-Mediated Necroptosis in ER-Positive Breast Cancer and Amelanotic Melanoma Cells. Cell Physiol Biochem. 54 (4): 591-604 (2020)
  5. Yang K., A.S.W. Oak, R.M. Slominski, A.A. Brożyna, A.T. Slominski: Current Molecular Markers of Melanoma and Treatment Targets. Int J Mol Sci. 21 (10): 3535 (2020)
  6. Oak A.S.W., G. Bocheva , T.K. Kim, A.A. Brożyna, Z. Janjetovic, M. Athar, R.C. Tuckey, A.T. Slominski: Noncalcemic Vitamin D Hydroxyderivatives Inhibit Human Oral Squamous Cell Carcinoma and Down-regulate Hedgehog and WNT/β-Catenin Pathways. Anticancer Res. 40 (5): 2467-2474 (2020)
  7. Slominski A.T., A.A. Brożyna, M.A. Zmijewski, Z. Janjetovic, T.K. Kim, R.M. Slominski, R.C. Tuckey, R.S. Mason, A.M. Jetten, P. Guroji, J. Reichrath, C. Elmets, M. Athar: The Role of Classical and Novel Forms of Vitamin D in the Pathogenesis and Progression of Nonmelanoma Skin Cancers. Adv Exp Med Biol. 1268: 257-283 (2020)
  8. Brożyna A.A., R.M. Hoffman, A.T. Slominski: Relevance of Vitamin D in Melanoma Development, Progression and Therapy. Anticancer Res. 40 (1): 473-489 (2020)
  9. Pawlikowska M., J. Piotrowski, T. Jędrzejewski, W. Kozak, A.T. Slominski, A.A. Brożyna: Coriolus versicolor-derived protein-bound polysaccharides trigger the caspase-independent cell death pathway in amelanotic but not melanotic melanoma cells. Phytother Res. 34 (1): 173-183 (2020)
  10. Kuźbicki Ł., A.A. Brożyna: Immunohistochemical detectability of cyclooxygenase-2 expression in cells of human melanocytic skin lesions: A methodological review. J Cutan Pathol. 47 (4): 363-380 (2020)

2019

  1. Pawlikowska M., J. Piotrowski, T. Jędrzejewski, W. Kozak, A.T. Slominski, A.A. Brożyna: Coriolus versicolor-derived protein-bound polysaccharides trigger the caspase-independent cell death pathway in amelanotic but not melanotic melanoma cells. Phytother Res. doi: 10.1002/ptr.6513 (2019)
  2. Brożyna A.A., W. Jóźwicki, A.M. Jetten, A.T. Slominski: On the relationship between VDR, RORα and RORγ receptors expression and HIF1-α levels in human melanomas. Exp Dermatol. 28 (9): 1036-1043 (2019)
  3. Markiewicz A., A.A. Brożyna, E. Podgórska, M. Elas, K. Urbańska, A.M. Jetten, A.T. Slominski, W. Jóźwicki, J. Orłowska-Heitzman, G. Dyduch, B. Romanowska-Dixon: Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels. Sci Rep. 9 (1): 9142 (2019)
  4. Linowiecka K., O. Urbanowska-Domańska, J. Guz, M. Foksiński: Breast cancer estrogen receptors influence on possible epigenetic implications in DNA. Contemp Oncol. 23 (2): 74-80 (2019)

2018

  1. Slominski A.T., T.K. Kim, Z. Janjetovic, A.A. Brożyna, M.A. Żmijewski, H. Xu, T.R. Sutter, R.C. Tuckey, A.M. Jetten, D.K. Crossman: Differential and Overlapping Effects of 20,23(OH)2D3 and 1,25(OH)2D3 on Gene Expression in Human Epidermal Keratinocytes: Identification of AhR as an Alternative Receptor for 20,23(OH)2D3. Int J Mol Sci. 19 (10) pii: E3072 (2018)
  2. Skobowiat C., A.A. Brożyna, Z. Janjetovic, S. Jeayeng, A.S.W. Oak, T.-K. Kim, U. Panich, R.J. Reiter, A.T. Słomiński: Melatonin and its derivatives counteract the ultraviolet B radiation-induced damage in human and porcine skin ex vivo. J. Pineal Res. 65 (2): e12501, 1-16. (2018)
  3. Slominski A.T., A.A. Brożyna, C. Skobowiat, M.A. Żmijewski, T.-K. Kim, Z. Janjetovic, A.S. Oak, W. Jóźwicki, A.M. Jetten, R.S. Mason, C. Elmets, W. Li, R.M. Hoffman, R.C. Tuckey: On the role of classical and novel forms of vitamin D in melanoma progression and management. J. Steroid Biochem. Mol. Biol. 177: 159-170 (2018)
  4. Śniegocka M., E. Podgórska, P.M. Płonka, M. Elas, B. Romanowska-Dixon, M. Szczygieł, M.A. Żmijewski, M. Cichorek, A. Markiewicz, A.A. Brożyna, A.T. Słomiński, K. Urbańska. Transplantable melanomas in hamsters and gerbils as models for human melanoma: sensitization in melanoma radiotherapy – from animal models to clinical trials. Int. J. Mol. Sci. 19 (4): 1048, 1-29 (2018)
  5. Kuźbicki Ł., D. Lange, A. Stanek-Widera, A. Glińska, B.W. Chwirot: Enhanced intratumoral expression of RNF2 is a favorable prognostic factor for patients with cutaneous melanoma? Oncotarget. 9 (25): 17656-17663 (2018)
  6. Starczak M., E. Zarakowska, M. Modrzejewska, T. Dziaman, A. Szpila, K. Linowiecka, J. Guz, J. Szpotan, M. Gawroński, A. Labejszo, A. Liebert, Z. Banaszkiewicz, M. Kłopocka, M. Foksiński, D. Gackowski, R. Oliński: In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease. J Transl Med. 16 (1): 204 doi: 10.1186/s12967-018-1581-9 (2018)
  7. Dziaman T., D. Gackowski, J. Guz, K. Linowiecka, M. Bodnar, M. Starczak, E. Zarakowska, M. Modrzejewska, A. Szpila, J. Szpotan, M. Gawroński, A. Łabejszo, A. Liebert, Z. Banaszkiewicz, M. Kłopocka, M. Foksiński, A. Marszałek, R. Oliński: Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions: benign adenomas and inflammatory bowel disease. Clin Epigenetics. 10: 72 doi: 10.1186/s13148-018-0505-0 (2018)

2017

  1. Kuźbicki Ł., D. Lange, A. Stanek-Widera, B.W. Chwirot: Prognostic significance of RBP2-H1 variant of JARID1B in melanoma. BMC Cancer. 17 (854) https://doi.org/10.1186/s12885-017-3836-x (2017)
  2. Slominski A.T., A.A. Brożyna, R.C. Tuckey: Cutaneous glucocorticoidogenesis and cortisol signaling are defective in psoriasis. J. Invest. Dermatol. 137 (8): 1609-1611 (2017)
  3. Brożyna A.A, H. Guo, S.-E. Yang, L. Cornelius, G. Linette, M. Murphy, C. Sheehan, J. Ross, A. Słomiński, J.A. Carlson. TRPM1 (melastatin) expression is an independent predictor of overall survival in clinical AJCC stage I and II melanoma patients. J. Cutan. Pathol. 44 (4): 328-337 (2017)
  4. Slominski A.T., A.A. Brożyna, M.A. Żmijewski, W. Jóźwicki, A.M. Jetten, R.S. Mason, R.C. Tuckey, C.A. Elmets. Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management. Lab. Invest. 97 (6): 706-724 (2017)

2016

  1. Kuźbicki Ł., D. Lange, A. Stanek-Widera, B.W. Chwirot: Intratumoral expression of cyclooxygenase-2 (COX-2) is a negative prognostic marker for patients with cutaneous melanoma. Melanoma Res. 26 (5) 448-456 (2016)
  2. Kuźbicki Ł., D. Lange, A. Strączyńska-Niemiec, B.W. Chwirot: Altered splicing of JARID1B in development of human cutaneous melanoma? Appl Immunohistochem Mol Morphol. 24 (3): 188-192 (2016)

2014

  1. Kuźbicki Ł., J. Urban, B.W. Chwirot: Different detectability of cyclooxygenase-2 (COX-2) protein in standard paraffin sections and tissue microarrays of human melanomas and naevi – Comparative study. Pathol Res Pract. 210 (9): 591-595 (2014)
  2. Urban J., Ł. Kuźbicki, G. Szatkowski, A. Stanek-Widera, D. Lange, B.W. Chwirot: Stromal, rather than epithelial cyclooxygenase-2 (COX-2) expression is associated with overall survival of breast cancer patients. BMC Cancer. 14 (732) https://doi.org/10.1186/1471-2407-14-732 (2014)

2013

  1. Kuźbicki Ł., D. Lange, A. Strączyńska-Niemiec, B.W. Chwirot: JARID1B expression in human melanoma and benign melanocytic skin lesions. Melanoma Res. 23 (1): 8-12 (2013)

2012

  1. Kuźbicki Ł., D. Lange, A. Strączyńska-Niemiec, B.W. Chwirot: The value of cyclooxygenase-2 expression in differentiating between early melanomas and histopathologically difficult types of benign human skin lesions. Melanoma Res. 22 (1): 70-76 (2012)

2011

  1. Kuźbicki Ł., D. Lange, A. Stanek-Widera, B.W. Chwirot: Different expression of cyclooxygenase-2 (COX-2) in selected nonmelanocytic human cutaneous lesions. Folia Histochem Cytobiol. 49 (3): 381-388 (2011)
  2. Chwirot B.W., J. Urban, Ł. Kuźbicki: Cyclooxygenase-2 overexpression as indicator of favorable clinicopathological phenotype and better survival of colorectal cancer patients: Fact or artifact? Basic & Applied Pathology 4: 33 (2011)

2010

  1. Kuźbicki Ł., D. Lange, A. Stanek-Widera, B.W. Chwirot: Cyclin-dependent kinase (CDK-2) expression in non-melanocytic human cutaneous lesions. Appl Immunohistochem Mol Morphol. 18 (4): 357-364 (2010)
  2. Sztramska A., M. Piwiński, B.W. Chwirot: Quantitative measurements of formalin-induced fluorescence for differential diagnostics of melanomas and lesions of human skin. Melanoma Res. 20 (5): 408-416 (2010)

2009

  1. Kuźbicki Ł., D. Lange, B.W. Chwirot: Cyclooxygenase-2 immunohistochemistry in human melanoma: differences between results obtained with different antibodies. Melanoma Res. 19 (5): 294-300 (2009)

2008

  1. Sztramska A., D. Dymerska, B.W. Chwirot: Skin layer-specific Melan-A expression during progression of human cutaneous melanoma: implications for diagnostic applications of the marker. Melanoma Res. 18 (4): 259-267 (2008)
  2. Brożyna A., L. VanMiddlesworth, A. Slominski: Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy, Int. J. Cancer. 123 (6):1448-1456 (2008)

2007

  1. Brożyna A., B. Zbytek, J. Granese, C.J. Andrew, J. Ross, A. Slominski: Mechanism of UV-related carcinogenesis and its contribution to nevi/melanoma. Expert. Rev. Dermatol. 2 (4): 451-469 (2007)
  2. Chwirot B.W., Ł. Kuźbicki: Cyclooxygenase-2 (COX-2): first immunohistochemical marker distinguishing early cutaneous melanomas from benign melanocytic skin tumours. Melanoma Res. 17 (3): 139-145 (2007)

2006

  1. Kuźbicki Ł., E. Aładowicz, B.W. Chwirot: Cyclin-dependent kinase 2 expression in human melanomas and benign melanocytic skin lesions. Melanoma Res. 16 (5): 435-444 (2006)
  2. Kuźbicki Ł., B. Gajo, B.W. Chwirot: Different expression of lysosome-associated membrane protein-1 in human melanomas and benign melanocytic lesions. Melanoma Res. 16 (3): 235-243 (2006)
  3. Kuźbicki Ł., A. Sarnecka, B.W. Chwirot: Expression of cyclooxygenase-2 in benign nevi and during human cutaneous melanoma progression. Melanoma Res. 16 (1): 29-36 (2006)
  4. Brożyna A., B.W. Chwirot: Porcine Skin As a Model System for Studies of Ultraviolet A Effects in Human Skin, J. Toxicol. Environ. Health A 69, 1155-1165 (2006)

2005

  1. Niedojadło K., K. Łabędzka, E. Łada, A. Milewska, B.W. Chwirot: Apaf-1 expression in human cutaneous melanoma progression and in pigmented nevi. Pigment Cell Res. 19, 43-50 (2005)
  2. Chwirot B.W. i S. Chwirot: Endogenous fluorescence – new approach to in situ detection of premalignant and malignant lesions in human organs. Proc. SPIE 5849, 47-55 (2005)
  3. Brożyna A. i B.W. Chwirot: Different susceptibility of cells of porcine skin and internal organs to ultraviolet A-induced breaking of nuclear DNA. Photochem. Photobiol. 81, 674-681 (2005)

2004

  1. Chwirot B.W., S. Chwirot: Piętnaście lat badań nad zastosowaniem autofluorescencji komórek i tkanek do wykrywania zmian przednowotworowych i nowotworów u człowieka. Rozdział 5 w H. Podbielska, A. Sieroń, W. Stręk (red.): Diagnostyka i terapia fotodynamiczna. Wydawnictwo Medyczne Urban & Partner, Wrocław (2004)

2003

  1. Chwirot B.W., M. Kowalska, N. Płóciennik, M. Piwiński, Z. Michniewicz, S. Chwirot: Variability of spectra of laser-induced fluorescence of colonic mucosa: Its significance for fluorescence detection of colonic neoplasia. Ind. J. Exp. Biol. 41, 500-510 (2003)

2002

  1. Chwirot B.W., S. Chwirot: Fluorescence detection of human tumours without photosensitisers. Optica Applicata, Vol. XXXII, No. 4 (2002)
  2. Chwirot B.W., N. Sypniewska, E. Barcikowska: Quantitative measurements of the fluorescence intensity – new method for a detection of melanoma cells in histopathological preparations. Optica Applicata, Vol. XXXII, No. 4 (2002)

2001

  1. Chwirot B.W., N. Sypniewska, J. Światlak: Diagnostic potential of fluorescence of formalin – fixed paraffin – embedded malignant melanoma and pigmented skin lesions. Quantitative study of fluorescence intensity using fluorescence microscope and digital imaging. Melanoma Res 11, 569-576 (2001)
  2. Chwirot B.W., S. Chwirot, N. Sypniewska, Z. Michniewicz, J. Redziński, G. Kurzawski, W. Ruka: Fluorescence in situ Detection of Human Cutaneous Melanoma: Study of Diagnostic Parameters of the Method. – J. Invest. Dermatol. 117, 1449-1451 (2001)

1999

  1. Chwirot B.W., M. Kowalska, N. Sypniewska, Z. Michniewicz, M. Grądziel: Spectrally Resolved Fluorescence Imaging of Human Colonic Adenomas. J. Photochem. Photobiol. B: Biol. 50, 174-183 (1999)
  2. Chwirot B.W., Z. Michniewicz, M. Kowalska, J. Nussbeutel: Detection of Colonic Malignant Lesions by Digital Imaging of Ultraviolet Laser – Induced Autofluorescence. Photochem. Photobiol. 69, 336-340 (1999)

Conference abstracts and other studies

2023

  1. Mijewski P., E. Zarakowska, A. Wasilów, J. Szpotan, D. Gackowski, M. Foksiński, R. Oliński: DNA demethylation modifications and intracellular vitamin C level inside prostate tissues. 1st Epigenetics Society International Meeting “Epigenetics of Disease and Development”. Rome, Italy, October 12-14, 2023, Lausanne, Frontiers Media SA, 252-253 (2023)

2022

  1. Mijewski P., E. Zarakowska, A. Wasilów, D.Gackowski, J. Guz, J. Szpotan, K. Linowiecka, M. Foksiński: The impact of chemotherapy on DNA demethylation modifications and intracellular vitamin C levels in women with breast cancer. XXVI Gliwice Scientific Meetings. Gliwice, November 18-19, 2022, abstract, 120 (2022)

2021

  1. Siomek-Górecka A., S. Stawieraj, D. Gackowski, K. Koszucka, J. Szpotan: Possible role of vitamins A and E as an epigenetic modulators. The 6th International Vitamin Conference, Kopenhaga September 22-24, 2021, abstract, 33 (2021)
  2. Linowiecka K., J. Szpotan, K. Koszucka, E. Zarakowska, A. Szpila, D. Gackowski, M. Foksiński: Vitamin C and its connections to DNA demethylation in breast carcinogenesis. The 6th International Vitamin Conference, Kopenhaga 22-24 września 2021, abstract, 61 (2021)
  3. Dziarkowska M., M. Racka, I. Permoda, K. Wiśniak, Ł. Kuźbicki, A.A. Brożyna: TRIM37 – nowy marker prognostyczny w czerniakach skóry człowieka?, Badania i Rozwój Młodych Naukowców w Polsce 2021, materiały konferencyjne – wiosna, s. 18, Młodzi Naukowcy, Poznań (2021)
  4. Wiśniak K., I. Permoda, M. Racka, M. Dziarkowska, Ł. Kuźbicki, A.A. Brożyna: Próba oceny przydatności prognostycznej RNF2 i TRIM37 w czerniakach skóry człowieka, Badania i Rozwój Młodych Naukowców w Polsce 2021, materiały konferencyjne – wiosna, s. 55, Młodzi Naukowcy, Poznań (2021)

2013

  1. Urban J., Ł. Kuźbicki, B.W. Chwirot: Stromal COX-2 expression as a marker of human breast cancer invasiveness. Acta Biochim Pol. 60, S1 113 (2013)
  2. Kuźbicki Ł., D. Lange, A. Strączyńska-Niemiec, B.W. Chwirot: Diagnostic potential of JARID1B expression in differentiating between early melanomas and benign human skin lesions. Acta Biochim Pol. 60 S1 106 (2013)

2012

  1. Kuźbicki Ł, J. Urban, B.W. Chwirot: Immunohistochemiczna wykrywalność ekspresji cyklooksygenazy-2 (COX-2) w mikromacierzach tkankowych i standardowych preparatach histopatologicznych jako markera czerniaka u człowieka. Post Biol Kom. 39 S27 40 (2012)
  2. Urban J., Ł. Kuźbicki, B.W. Chwirot: Ekspresja cyklooksygenazy 2 (COX-2) w makrofagach jako potencjalny marker prognostyczny w nowotworach jelita grubego człowieka. Post Biol Kom. 39 S27 29 (2012)
  3. Szatkowski G., D. Dziczek, B.W. Chwirot: Ocena podatności komórek ściany tętnicy udowej szczura na indukcję pęknięć jądrowego DNA impulsowym promieniowaniem UVB i kinetyki ich naprawy. Post Biol Kom. 39, S27 32 (2012)

2011

  1. Kuźbicki Ł., D. Lange, A. Strączyńska-Niemiec, B.W. Chwirot: Diagnostic potential of cyclooxygenase-2 immunohistochemical expression for differentiating between melanocytic naevi and early human cutaneous melanomas. Wsp Onkol. 15 S1 94-95 (2011)
  2. Urban J., Ł. Kuźbicki, B.W. Chwirot: Ekspresja cyklooksygenazy 2 (COX-2) w nowotworach piersi człowieka. Wsp Onkol. 15 S1 99 (2011)
  3. Urban J., B.W. Chwirot: Epithelial and stromal COX-2 expression as a potential marker of progression of human breast tumors. Acta Biochim Pol. 58 S2 77 (2011)
  4. Szatkowski G., D. Dziczek, Ł. Kuźbicki, G. Sworowski, B.W. Chwirot: Susceptibility of cells of rat femoral artery wall to ultraviolet UVB light – induced breaking of nuclear DNA. Acta Biochim Pol. 58 S2 288 (2011)

2010

  1. Szatkowski G., D. Dziczek, B.W. Chwirot: Biological effects of irradiation of rat blood vessel cells with 308 nm pulses of Xe-Cl excimer laser – design of experiment and first results. Curr Top Biophys. 33 Suppl. B 55 (2010)

2009

  1. Kuźbicki Ł., D. Lange, D. Słowińska, J. Urban, G. Szatkowski, B.W. Chwirot: Cyclooxygenase-2 (COX-2) expression in human melanocytic nevi and cutaneous melanomas – immunohistochemistry with two different types of antibodies. Med. Biol. Sci. 23 S2, 37 (2009)
  2. Kuźbicki Ł., D. Lange, E. Róg-Zielińska, J. Rzemek, B.W. Chwirot: Cyclooxygenase (COX-2) expression in selected nonmelanocytic human skin lesions. Med. Biol. Sci. 23 S2, 36-37 (2009)
  3. Kuźbicki Ł., D. Lange, A. Piksa, A. Misz, B.W. Chwirot: Different expression of cyclin-dependent kinase 2 (CDK-2) in benign and malignant nonmelanocytic human skin lesions. Med. Biol. Sci. 23 S2, 36 (2009)

2005

  1. Sztramska A., B. Dybciak, B.W. Chwirot: Formalin-induced fluorescence of human malignant melanoma and benign pigmented skin lesions. Folia Histochem. Cytobiol. 43 S1, 73-74 (2005)
  2. Niedojadło K., E. Łada, A. Milewska, B.W. Chwirot: Apaf-1 expression in human skin, pigmented lesions, melanomas and melanoma lymph node metastases. Folia Histochem. Cytobiol. 43 S1, 65-66 (2005)
  3. Kuźbicki Ł., A. Sarnecka, B.W. Chwirot: Expression of cyclooxygenase 2 in human malignant and benign melanocytic tumours. Folia Histochem. Cytobiol. 43 S1, 61 (2005)
  4. Kuźbicki Ł., E. Aładowicz, B.W. Chwirot: Differences in expression of CDK-2 in cutaneous melanomas and benign melanocytic lesions in human. Folia Histochem. Cytobiol. 43 S1, 60-61 (2005)
  5. Brożyna A., K. Fidos, B.W. Chwirot: Different efficiency of UV-induction of DNA breaks by pulsed and continuously delivered laser radiation. Folia Histochem. Cytobiol. 43 S1, 51-52 (2005)

2002

  1. Sypniewska N., E. Barcikowska, B.W. Chwirot: Formalin – induced fluorescence (FIF) as an auxiliary tool for the histopathological diagnosis of human cutaneous melanoma. Cell. Mol. Biol. Lett. 7, 107 (2002)
  2. Brożyna A., K. Kwiatkowska, B.W. Chwirot: The induction of nuclear DNA breaks in human skin cells by ultraviolet A (UVA) light. Cell. Mol. Biol. Lett. 7, 86 (2002)
  3. Chwirot B.W., S. Chwirot, N. Sypniewska: Fluorescence in situ detection of human cutaneous melanoma: diagnostic parameters of the method. Pigment Cell Res. 15 (S9), 43 (2002)
  4. Sypniewska N., B.W. Chwirot, E. Barcikowska: Significant difference in intensity of formalin – induced fluorescence of melanomas in horizontal and vertical growth phase. Pigment Cell Res. 15 (S9), 67 (2002)

2000

  1. Chwirot B.W., M. Kowalska, N. Sypniewska, Z. Michniewicz, M. Grądziel: Spectrally resolved imaging of UV laser – excited fluorescence of human colonic adenomas. str. 93-98 w R. Maniewski, G. Nilson i H. Wierzba (red.): Optoelectronics in Medical Diagnosis. Lecture Notes of the ICB Seminars, Międzynarodowe Centrum Biocybernetyki PAN – WHO, Warszawa (2000)

1999

  1. Chwirot B.W., N. Sypniewska, M. Grądziel, M. Piwiński: In vitro autofluorescence of human skin: contribution of individual skin layers. Folia Histochem. Cytobiol. 37S1, 9 (1999)
  2. Chwirot B.W., M. Kowalska, M. Grądziel, Z. Michniewicz: Fluorescence microscopic studies on localisation and nature of native fluorophores in normal mucosa and malignant lesions of human colon. Folia Histochem. Cytobiol. 37S1, 8 (1999)
  3. Chwirot B.W., M. Jackowski, A. Brożyna, M. Piwiński: Optical biopsy of lesions and normal mucosa in human stomach: in vivo and in vitro study. Folia Histochem. Cytobiol. 37S1, 8 (1999)